STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Huta_1416PFAM: DEAD_2 domain protein; SMART: helicase c2; Helicase-like, DEXD box c2 type; DEAD-like helicases; KEGG: hma:rrnAC2719 helicase. (722 aa)    
Predicted Functional Partners:
Huta_2465
SMART: helicase c2; Helicase-like, DEXD box c2 type; DEAD-like helicases; KEGG: hma:rrnAC0680 helicase.
  
  
 
0.921
Huta_0308
PFAM: type III restriction protein res subunit; helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; helicase domain protein; KEGG: hma:rrnAC0617 DNA repair protein Rad25.
   
 0.887
Huta_2521
PFAM: RNA polymerase insert; RNA polymerase dimerisation; SMART: RNA polymerase RpoA/D/Rpb3-type; KEGG: hma:rrnAC0062 DNA-directed RNA polymerase subunit D.
  
 
 0.877
tfe
Transcription factor TFIIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongatio [...]
   
 0.873
rpoH
RNA polymerase Rpb5; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family.
    
 0.835
rpoK
RNA polymerase Rpb6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family.
    
 0.834
rpoN
RNA polymerase, N/8 Kd subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family.
    
 0.834
rpoP
RNA polymerase Rbp10; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family.
    
 0.834
uvrC
Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
  
 0.691
pcn
Proliferating cell nuclear antigen, PCNA; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
  
 
 0.686
Your Current Organism:
Halorhabdus utahensis
NCBI taxonomy Id: 519442
Other names: H. utahensis DSM 12940, Halorhabdus utahensis AX-2, Halorhabdus utahensis DSM 12940, Halorhabdus utahensis str. DSM 12940, Halorhabdus utahensis strain DSM 12940
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.