Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Huta_1663TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: hma:rrnAC2962 putative haloacid dehalogenase- like hydrolase. (213 aa)    
Predicted Functional Partners:
Huta_1052
PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: hma:rrnAC1962 putative alpha-D-14-glucosidase.
 
  
 0.662
Huta_1668
PFAM: DNA topoisomerase type IA zn finger domain protein; KEGG: hma:rrnAC2963 topoisomerase DNA binding C4 zinc finger.
       0.651
Huta_1156
SPP-like hydrolase; Catalyzes the dephosphorylation of 2-phosphoglycolate.
 
  
 0.645
mre11
Metallophosphoesterase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity; Belongs to the MRE11/RAD32 family.
       0.570
Huta_1664
KEGG: hma:rrnAC2115 hypothetical protein.
       0.563
endA
tRNA intron endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
       0.556
Huta_1471
TIGRFAM: glycerol-3-phosphate dehydrogenase, anaerobic, A subunit; PFAM: FAD dependent oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: hma:rrnAC0554 glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
  
  
 0.529
Huta_1475
KEGG: hma:rrnAC0546 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
  
 
 0.506
Huta_2626
Alanine--glyoxylate transaminase; PFAM: aminotransferase class V; KEGG: hwa:HQ2919A aminotransferase class V (serine-- pyruvate aminotransferase 2; alanine--glyoxylate aminotransferase 2).
     
 0.459
Huta_0650
KEGG: hma:rrnAC0342 1-phosphofructokinase; TIGRFAM: 1-phosphofructokinase; PFAM: PfkB domain protein.
 
    0.412
Your Current Organism:
Halorhabdus utahensis
NCBI taxonomy Id: 519442
Other names: H. utahensis DSM 12940, Halorhabdus utahensis AX-2, Halorhabdus utahensis DSM 12940, Halorhabdus utahensis str. DSM 12940, Halorhabdus utahensis strain DSM 12940
Server load: low (14%) [HD]