Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Huta_2000KEGG: hwa:HQ2423A 6-pyruvoyltetrahydropterin synthase. (130 aa)    
Predicted Functional Partners:
Huta_2001
KEGG: hsl:OE2497F hypothetical protein.
 
     0.981
Huta_1999
PFAM: Alcohol dehydrogenase zinc-binding domain protein; KEGG: hwa:HQ2425A oxidoreductase (Zn-dependent dehydrogenases, threonine 3-dehydrogenase).
 
     0.971
gch3
GTP cyclohydrolase IIa; Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity; Belongs to the archaeal-type GTP cyclohydrolase family.
 
     0.846
Huta_1995
PFAM: CDP-alcohol phosphatidyltransferase; KEGG: hma:pNG7099 CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
     0.768
truA
tRNA pseudouridine synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family.
 
     0.694
cysS
KEGG: hma:rrnAC1292 cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M).
   
  
 0.574
Huta_1997
PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related; KEGG: hma:rrnAC3274 glucose-6-phosphatase.
       0.492
mptA
GTP cyclohydrolase MptA; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
     
 0.484
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
    
   0.482
thrS
TIGRFAM: threonyl-tRNA synthetase; PFAM: Threonyl-tRNA synthetase editing domain protein; tRNA synthetase class II (G H P and S); Anticodon- binding domain protein; KEGG: mem:Memar_0766 threonyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
   
 
 0.472
Your Current Organism:
Halorhabdus utahensis
NCBI taxonomy Id: 519442
Other names: H. utahensis DSM 12940, Halorhabdus utahensis AX-2, Halorhabdus utahensis DSM 12940, Halorhabdus utahensis str. DSM 12940, Halorhabdus utahensis strain DSM 12940
Server load: low (16%) [HD]