STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Huta_2284PFAM: peptidase S1 and S6 chymotrypsin/Hap; KEGG: hwa:HQ1855A serine proteinase. (367 aa)    
Predicted Functional Partners:
Huta_2751
PFAM: peptidase S1 and S6 chymotrypsin/Hap; KEGG: hma:rrnAC0296 serine protease HtrA.
  
  
 
0.905
pan
26S proteasome subunit P45 family; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...]
    
 0.740
Huta_1160
26S proteasome subunit P45 family; KEGG: hma:rrnAC3190 proteasome-activating nucleotidase; TIGRFAM: 26S proteasome subunit P45 family; PFAM: AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; Belongs to the AAA ATPase family.
    
 0.740
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
   
 0.656
dnaK
Chaperone protein DnaK; Acts as a chaperone.
 
 
 0.598
Huta_1567
PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: mgi:Mflv_1887 two component transcriptional regulator.
 
  
 0.580
Huta_2490
PFAM: MaoC domain protein dehydratase; KEGG: nph:NP2256A enoyl-CoA hydratase II 3.
    
  0.533
Huta_2528
Cobyrinic acid ac-diamide synthase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
 
  
 0.478
rps12
Ribosomal protein S23 (S12); With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.
 
 
 0.469
Huta_0716
Proteasome Rpn11 subunit JAMM motif protein; KEGG: hma:rrnAC1439 hypothetical protein.
   
 0.467
Your Current Organism:
Halorhabdus utahensis
NCBI taxonomy Id: 519442
Other names: H. utahensis DSM 12940, Halorhabdus utahensis AX-2, Halorhabdus utahensis DSM 12940, Halorhabdus utahensis str. DSM 12940, Halorhabdus utahensis strain DSM 12940
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