node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFR41040.1 | SFR41049.1 | SAMN04488070_0639 | SAMN04488070_0640 | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 23S rRNA (uracil1939-C5)-methyltransferase. | 0.933 |
SFR41040.1 | SFR41066.1 | SAMN04488070_0639 | SAMN04488070_0642 | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | DNA replication and repair protein RecO. | 0.812 |
SFR41040.1 | SFR41090.1 | SAMN04488070_0639 | SAMN04488070_0645 | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Signal peptidase I. Serine peptidase. MEROPS family S26A. | 0.872 |
SFR41040.1 | era | SAMN04488070_0639 | SAMN04488070_0643 | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.900 |
SFR41040.1 | lepA | SAMN04488070_0639 | SAMN04488070_0646 | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.821 |
SFR41040.1 | pdxJ | SAMN04488070_0639 | SAMN04488070_0641 | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Pyridoxine 5-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.809 |
SFR41040.1 | rnc | SAMN04488070_0639 | SAMN04488070_0644 | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | RNAse III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.815 |
SFR41049.1 | SFR41040.1 | SAMN04488070_0640 | SAMN04488070_0639 | 23S rRNA (uracil1939-C5)-methyltransferase. | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.933 |
SFR41049.1 | SFR41066.1 | SAMN04488070_0640 | SAMN04488070_0642 | 23S rRNA (uracil1939-C5)-methyltransferase. | DNA replication and repair protein RecO. | 0.834 |
SFR41049.1 | SFR41090.1 | SAMN04488070_0640 | SAMN04488070_0645 | 23S rRNA (uracil1939-C5)-methyltransferase. | Signal peptidase I. Serine peptidase. MEROPS family S26A. | 0.804 |
SFR41049.1 | era | SAMN04488070_0640 | SAMN04488070_0643 | 23S rRNA (uracil1939-C5)-methyltransferase. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.829 |
SFR41049.1 | lepA | SAMN04488070_0640 | SAMN04488070_0646 | 23S rRNA (uracil1939-C5)-methyltransferase. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.856 |
SFR41049.1 | pdxJ | SAMN04488070_0640 | SAMN04488070_0641 | 23S rRNA (uracil1939-C5)-methyltransferase. | Pyridoxine 5-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.807 |
SFR41049.1 | rnc | SAMN04488070_0640 | SAMN04488070_0644 | 23S rRNA (uracil1939-C5)-methyltransferase. | RNAse III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.832 |
SFR41066.1 | SFR41040.1 | SAMN04488070_0642 | SAMN04488070_0639 | DNA replication and repair protein RecO. | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.812 |
SFR41066.1 | SFR41049.1 | SAMN04488070_0642 | SAMN04488070_0640 | DNA replication and repair protein RecO. | 23S rRNA (uracil1939-C5)-methyltransferase. | 0.834 |
SFR41066.1 | SFR41090.1 | SAMN04488070_0642 | SAMN04488070_0645 | DNA replication and repair protein RecO. | Signal peptidase I. Serine peptidase. MEROPS family S26A. | 0.852 |
SFR41066.1 | SFR42861.1 | SAMN04488070_0642 | SAMN04488070_0882 | DNA replication and repair protein RecO. | Phosphate starvation-inducible protein PhoH. | 0.814 |
SFR41066.1 | era | SAMN04488070_0642 | SAMN04488070_0643 | DNA replication and repair protein RecO. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.983 |
SFR41066.1 | lepA | SAMN04488070_0642 | SAMN04488070_0646 | DNA replication and repair protein RecO. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.829 |