Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EHQ51162.1Cyclic nucleotide-binding protein; COG2905 Predicted signal-transduction protein containing cAMP-binding and CBS domains. (346 aa)    
Predicted Functional Partners:
EHQ51163.1
Sodium symporter protein; COG4147 Predicted symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
    0.938
EHQ52923.1
COG0067 Glutamate synthase domain 1.
    
 0.885
EHQ52810.1
Pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit.
    
  0.884
EHQ51164.1
COG4327 Predicted membrane protein.
 
     0.855
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
 0.796
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.787
EHQ53122.1
Acetate permease; COG4147 Predicted symporter; overlaps another CDS with the same product name; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
    0.733
EHQ53123.1
COG3162 Predicted membrane protein.
  
  
 0.644
actP
Acetate permease; COG4147 Predicted symporter; overlaps another CDS with the same product name; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
    0.629
acsA
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
    0.497
Your Current Organism:
Ectothiorhodospira sp. PHS1
NCBI taxonomy Id: 519989
Other names: E. sp. PHS-1, Ectothiorhodospira sp. PHS-1
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