| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EHQ51239.1 | EHQ51240.1 | ECTPHS_01024 | ECTPHS_01029 | Cobalamin biosynthesis protein precorrin-8X methylmutase; COG2082 Precorrin isomerase. | COG2243 Precorrin-2 methylase; Belongs to the precorrin methyltransferase family. | 0.996 |
| EHQ51239.1 | EHQ51241.1 | ECTPHS_01024 | ECTPHS_01034 | Cobalamin biosynthesis protein precorrin-8X methylmutase; COG2082 Precorrin isomerase. | COG1010 Precorrin-3B methylase. | 0.999 |
| EHQ51239.1 | EHQ51242.1 | ECTPHS_01024 | ECTPHS_01039 | Cobalamin biosynthesis protein precorrin-8X methylmutase; COG2082 Precorrin isomerase. | COG2099 Precorrin-6x reductase. | 0.990 |
| EHQ51239.1 | EHQ51243.1 | ECTPHS_01024 | ECTPHS_01044 | Cobalamin biosynthesis protein precorrin-8X methylmutase; COG2082 Precorrin isomerase. | Cobalamin(vitamin B12) biosynthesis protein precorrin-6Y C5,15-methyltransferase; COG2241 Precorrin-6B methylase 1. | 0.999 |
| EHQ51239.1 | EHQ51244.1 | ECTPHS_01024 | ECTPHS_01049 | Cobalamin biosynthesis protein precorrin-8X methylmutase; COG2082 Precorrin isomerase. | COG2875 Precorrin-4 methylase; Belongs to the precorrin methyltransferase family. | 0.990 |
| EHQ51239.1 | EHQ51294.1 | ECTPHS_01024 | ECTPHS_01299 | Cobalamin biosynthesis protein precorrin-8X methylmutase; COG2082 Precorrin isomerase. | Precorrin 6A synthase; COG2243 Precorrin-2 methylase. | 0.977 |
| EHQ51239.1 | EHQ52524.1 | ECTPHS_01024 | ECTPHS_07526 | Cobalamin biosynthesis protein precorrin-8X methylmutase; COG2082 Precorrin isomerase. | Sirohydrochlorin cobaltochelatase; COG4822 Cobalamin biosynthesis protein CbiK, Co2+ chelatase. | 0.744 |
| EHQ51239.1 | cobQ | ECTPHS_01024 | ECTPHS_01074 | Cobalamin biosynthesis protein precorrin-8X methylmutase; COG2082 Precorrin isomerase. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.921 |
| EHQ51239.1 | cobQ-2 | ECTPHS_01024 | ECTPHS_01079 | Cobalamin biosynthesis protein precorrin-8X methylmutase; COG2082 Precorrin isomerase. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.934 |
| EHQ51239.1 | cobS | ECTPHS_01024 | ECTPHS_05756 | Cobalamin biosynthesis protein precorrin-8X methylmutase; COG2082 Precorrin isomerase. | Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.547 |
| EHQ51240.1 | EHQ51239.1 | ECTPHS_01029 | ECTPHS_01024 | COG2243 Precorrin-2 methylase; Belongs to the precorrin methyltransferase family. | Cobalamin biosynthesis protein precorrin-8X methylmutase; COG2082 Precorrin isomerase. | 0.996 |
| EHQ51240.1 | EHQ51241.1 | ECTPHS_01029 | ECTPHS_01034 | COG2243 Precorrin-2 methylase; Belongs to the precorrin methyltransferase family. | COG1010 Precorrin-3B methylase. | 0.999 |
| EHQ51240.1 | EHQ51242.1 | ECTPHS_01029 | ECTPHS_01039 | COG2243 Precorrin-2 methylase; Belongs to the precorrin methyltransferase family. | COG2099 Precorrin-6x reductase. | 0.981 |
| EHQ51240.1 | EHQ51243.1 | ECTPHS_01029 | ECTPHS_01044 | COG2243 Precorrin-2 methylase; Belongs to the precorrin methyltransferase family. | Cobalamin(vitamin B12) biosynthesis protein precorrin-6Y C5,15-methyltransferase; COG2241 Precorrin-6B methylase 1. | 0.990 |
| EHQ51240.1 | EHQ51244.1 | ECTPHS_01029 | ECTPHS_01049 | COG2243 Precorrin-2 methylase; Belongs to the precorrin methyltransferase family. | COG2875 Precorrin-4 methylase; Belongs to the precorrin methyltransferase family. | 0.984 |
| EHQ51240.1 | EHQ51294.1 | ECTPHS_01029 | ECTPHS_01299 | COG2243 Precorrin-2 methylase; Belongs to the precorrin methyltransferase family. | Precorrin 6A synthase; COG2243 Precorrin-2 methylase. | 0.798 |
| EHQ51240.1 | EHQ52524.1 | ECTPHS_01029 | ECTPHS_07526 | COG2243 Precorrin-2 methylase; Belongs to the precorrin methyltransferase family. | Sirohydrochlorin cobaltochelatase; COG4822 Cobalamin biosynthesis protein CbiK, Co2+ chelatase. | 0.953 |
| EHQ51240.1 | cobQ | ECTPHS_01029 | ECTPHS_01074 | COG2243 Precorrin-2 methylase; Belongs to the precorrin methyltransferase family. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.850 |
| EHQ51240.1 | cobQ-2 | ECTPHS_01029 | ECTPHS_01079 | COG2243 Precorrin-2 methylase; Belongs to the precorrin methyltransferase family. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.875 |
| EHQ51240.1 | cobS | ECTPHS_01029 | ECTPHS_05756 | COG2243 Precorrin-2 methylase; Belongs to the precorrin methyltransferase family. | Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.591 |