Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EHQ51462.1COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. (150 aa)    
Predicted Functional Partners:
folE
COG0302 GTP cyclohydrolase I.
  
 
 0.868
EHQ52810.1
Pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit.
    
  0.832
folE2
Hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate.
  
  
  0.812
EHQ51461.1
Surface antigen variable number repeat-containing protein; COG4775 Outer membrane protein/protective antigen OMA87.
       0.768
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
 0.750
metH
B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.736
EHQ51421.1
Mutator MutT protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.
  
 
 0.733
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
     
  0.728
EHQ51060.1
COG0720 6-pyruvoyl-tetrahydropterin synthase.
     
  0.725
EHQ53304.1
Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
  0.725
Your Current Organism:
Ectothiorhodospira sp. PHS1
NCBI taxonomy Id: 519989
Other names: E. sp. PHS-1, Ectothiorhodospira sp. PHS-1
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