Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
dsbBCOG1495 Disulfide bond formation protein DsbB. (164 aa)    
Predicted Functional Partners:
EHQ52021.1
Thiol:disulfide interchange protein DsbC; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.
 
 
 0.927
EHQ51876.1
DSBA oxidoreductase; COG0526 Thiol-disulfide isomerase and thioredoxins.
 
  
 0.627
dsbD
Protein-disulfide reductase; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.
   
  
 0.588
EHQ52930.1
Periplasmic protein thiol/disulfide oxidoreductase DsbE; COG0526 Thiol-disulfide isomerase and thioredoxins.
     
 0.577
EHQ52150.1
COG4786 Flagellar basal body rod protein; Belongs to the flagella basal body rod proteins family.
    
   0.572
EHQ51226.1
Nitrogen fixation-like protein.
  
     0.527
EHQ52464.1
Hypothetical protein; COG0477 Permeases of the major facilitator superfamily.
       0.515
EHQ52465.1
Membrane protein, major facilitator transporter family protein; COG0477 Permeases of the major facilitator superfamily.
       0.515
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.514
EHQ51857.1
Hypothetical protein.
  
    0.514
Your Current Organism:
Ectothiorhodospira sp. PHS1
NCBI taxonomy Id: 519989
Other names: E. sp. PHS-1, Ectothiorhodospira sp. PHS-1
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