Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fniIsopentenyl pyrophosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (349 aa)    
Predicted Functional Partners:
EHQ52810.1
Pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit.
    
 0.961
EHQ51578.1
FAD linked oxidase domain-containing protein; COG0277 FAD/FMN-containing dehydrogenases.
  
 0.938
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.911
EHQ51062.1
COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
  
 
 0.904
ispH
Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
    
 0.892
EHQ51685.1
COG0281 Malic enzyme; Belongs to the malic enzymes family.
    
 0.875
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.858
EHQ53088.1
COG5016 Pyruvate/oxaloacetate carboxyltransferase.
     
  0.827
EHQ53237.1
Alanine--glyoxylate transaminase; COG0075 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase.
  
 0.824
EHQ52655.1
Geranylgeranyl reductase; COG0644 Dehydrogenases (flavoproteins).
  
  
 0.755
Your Current Organism:
Ectothiorhodospira sp. PHS1
NCBI taxonomy Id: 519989
Other names: E. sp. PHS-1, Ectothiorhodospira sp. PHS-1
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