Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EHQ52736.1COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4). (476 aa)    
Predicted Functional Partners:
EHQ51531.1
Serine-type D-Ala-D-Ala carboxypeptidase; COG1686 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
     
 0.902
ftsI
Peptidoglycan glycosyltransferase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
     
 0.877
mrdA
Peptidoglycan glycosyltransferase; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
  
  
 0.861
EHQ52322.1
Peptidoglycan glycosyltransferase; COG5009 Membrane carboxypeptidase/penicillin-binding protein.
     
 0.841
EHQ53140.1
Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
     
 0.841
mtgA
Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.
  
  
 0.826
EHQ53111.1
Beta-lactamase family protein; COG1680 Beta-lactamase class C and other penicillin binding proteins.
     
 0.801
EHQ52790.1
Hypothetical protein.
   
 
 0.790
nagZ
beta-N-acetylhexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
     
 0.617
EHQ52737.1
Late competence development protein ComFB; COG0013 Alanyl-tRNA synthetase.
       0.519
Your Current Organism:
Ectothiorhodospira sp. PHS1
NCBI taxonomy Id: 519989
Other names: E. sp. PHS-1, Ectothiorhodospira sp. PHS-1
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