EHQ52903.1 protein (Ectothiorhodospira sp. PHS1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

EHQ52903.1

A/G-specific DNA-adenine glycosylase; Adenine glycosylase active on G-A mispairs. (365 aa)

Predicted Functional Partners:

sfsA

0.932

EHQ52538.1

0.898

EHQ52532.1

0.862

EHQ52764.1

0.862

EHQ52904.1

0.841

EHQ52902.1

0.839

mutM

0.631

polA

0.631

mutL

0.589

lpxC

0.577

Your Current Organism:

Ectothiorhodospira sp. PHS1

NCBI taxonomy Id: 519989
Other names: E. sp. PHS-1, Ectothiorhodospira sp. PHS-1

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EHQ52532.1	EHQ52538.1	ECTPHS_07566	ECTPHS_07596	COG0708 Exonuclease III.	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.891
EHQ52532.1	EHQ52764.1	ECTPHS_07566	ECTPHS_08738	COG0708 Exonuclease III.	Exodeoxyribonuclease III Xth; COG0708 Exonuclease III.	0.837
EHQ52532.1	EHQ52903.1	ECTPHS_07566	ECTPHS_09433	COG0708 Exonuclease III.	A/G-specific DNA-adenine glycosylase; Adenine glycosylase active on G-A mispairs.	0.862
EHQ52532.1	polA	ECTPHS_07566	ECTPHS_12014	COG0708 Exonuclease III.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.635
EHQ52538.1	EHQ52532.1	ECTPHS_07596	ECTPHS_07566	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	COG0708 Exonuclease III.	0.891
EHQ52538.1	EHQ52764.1	ECTPHS_07596	ECTPHS_08738	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	Exodeoxyribonuclease III Xth; COG0708 Exonuclease III.	0.871
EHQ52538.1	EHQ52903.1	ECTPHS_07596	ECTPHS_09433	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	A/G-specific DNA-adenine glycosylase; Adenine glycosylase active on G-A mispairs.	0.898
EHQ52538.1	lpxC	ECTPHS_07596	ECTPHS_01909	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.	0.546
EHQ52538.1	mutL	ECTPHS_07596	ECTPHS_00390	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.	0.975
EHQ52538.1	polA	ECTPHS_07596	ECTPHS_12014	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.991
EHQ52764.1	EHQ52532.1	ECTPHS_08738	ECTPHS_07566	Exodeoxyribonuclease III Xth; COG0708 Exonuclease III.	COG0708 Exonuclease III.	0.837
EHQ52764.1	EHQ52538.1	ECTPHS_08738	ECTPHS_07596	Exodeoxyribonuclease III Xth; COG0708 Exonuclease III.	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.871
EHQ52764.1	EHQ52903.1	ECTPHS_08738	ECTPHS_09433	Exodeoxyribonuclease III Xth; COG0708 Exonuclease III.	A/G-specific DNA-adenine glycosylase; Adenine glycosylase active on G-A mispairs.	0.862
EHQ52764.1	polA	ECTPHS_08738	ECTPHS_12014	Exodeoxyribonuclease III Xth; COG0708 Exonuclease III.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.635
EHQ52902.1	EHQ52903.1	ECTPHS_09428	ECTPHS_09433	AsmA family protein; COG2982 Uncharacterized protein involved in outer membrane biogenesis.	A/G-specific DNA-adenine glycosylase; Adenine glycosylase active on G-A mispairs.	0.839
EHQ52902.1	EHQ52904.1	ECTPHS_09428	ECTPHS_09438	AsmA family protein; COG2982 Uncharacterized protein involved in outer membrane biogenesis.	Oxidative damage protection protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.	0.837
EHQ52903.1	EHQ52532.1	ECTPHS_09433	ECTPHS_07566	A/G-specific DNA-adenine glycosylase; Adenine glycosylase active on G-A mispairs.	COG0708 Exonuclease III.	0.862
EHQ52903.1	EHQ52538.1	ECTPHS_09433	ECTPHS_07596	A/G-specific DNA-adenine glycosylase; Adenine glycosylase active on G-A mispairs.	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.898
EHQ52903.1	EHQ52764.1	ECTPHS_09433	ECTPHS_08738	A/G-specific DNA-adenine glycosylase; Adenine glycosylase active on G-A mispairs.	Exodeoxyribonuclease III Xth; COG0708 Exonuclease III.	0.862
EHQ52903.1	EHQ52902.1	ECTPHS_09433	ECTPHS_09428	A/G-specific DNA-adenine glycosylase; Adenine glycosylase active on G-A mispairs.	AsmA family protein; COG2982 Uncharacterized protein involved in outer membrane biogenesis.	0.839