| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EHQ51092.1 | EHQ51685.1 | ECTPHS_00285 | ECTPHS_03272 | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | COG0281 Malic enzyme; Belongs to the malic enzymes family. | 0.857 |
| EHQ51092.1 | EHQ51693.1 | ECTPHS_00285 | ECTPHS_03312 | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase; COG2030 Acyl dehydratase. | 0.985 |
| EHQ51092.1 | EHQ52110.1 | ECTPHS_00285 | ECTPHS_05425 | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | propionate--CoA ligase; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. | 0.803 |
| EHQ51092.1 | EHQ52810.1 | ECTPHS_00285 | ECTPHS_08968 | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | Pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit. | 0.951 |
| EHQ51092.1 | EHQ53088.1 | ECTPHS_00285 | ECTPHS_10386 | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | COG5016 Pyruvate/oxaloacetate carboxyltransferase. | 0.870 |
| EHQ51092.1 | EHQ53497.1 | ECTPHS_00285 | ECTPHS_12545 | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | Acetyltransferase; COG1042 Acyl-CoA synthetase (NDP forming). | 0.868 |
| EHQ51092.1 | ackA | ECTPHS_00285 | ECTPHS_03307 | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.621 |
| EHQ51092.1 | acsA | ECTPHS_00285 | ECTPHS_00630 | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.892 |
| EHQ51685.1 | EHQ51092.1 | ECTPHS_03272 | ECTPHS_00285 | COG0281 Malic enzyme; Belongs to the malic enzymes family. | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.857 |
| EHQ51685.1 | EHQ51693.1 | ECTPHS_03272 | ECTPHS_03312 | COG0281 Malic enzyme; Belongs to the malic enzymes family. | Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase; COG2030 Acyl dehydratase. | 0.899 |
| EHQ51685.1 | EHQ52110.1 | ECTPHS_03272 | ECTPHS_05425 | COG0281 Malic enzyme; Belongs to the malic enzymes family. | propionate--CoA ligase; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. | 0.834 |
| EHQ51685.1 | EHQ52810.1 | ECTPHS_03272 | ECTPHS_08968 | COG0281 Malic enzyme; Belongs to the malic enzymes family. | Pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit. | 0.969 |
| EHQ51685.1 | EHQ52923.1 | ECTPHS_03272 | ECTPHS_09547 | COG0281 Malic enzyme; Belongs to the malic enzymes family. | COG0067 Glutamate synthase domain 1. | 0.706 |
| EHQ51685.1 | EHQ53088.1 | ECTPHS_03272 | ECTPHS_10386 | COG0281 Malic enzyme; Belongs to the malic enzymes family. | COG5016 Pyruvate/oxaloacetate carboxyltransferase. | 0.942 |
| EHQ51685.1 | EHQ53497.1 | ECTPHS_03272 | ECTPHS_12545 | COG0281 Malic enzyme; Belongs to the malic enzymes family. | Acetyltransferase; COG1042 Acyl-CoA synthetase (NDP forming). | 0.901 |
| EHQ51685.1 | ackA | ECTPHS_03272 | ECTPHS_03307 | COG0281 Malic enzyme; Belongs to the malic enzymes family. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.979 |
| EHQ51685.1 | acsA | ECTPHS_03272 | ECTPHS_00630 | COG0281 Malic enzyme; Belongs to the malic enzymes family. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.834 |
| EHQ51685.1 | purL | ECTPHS_03272 | ECTPHS_11150 | COG0281 Malic enzyme; Belongs to the malic enzymes family. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.740 |
| EHQ51693.1 | EHQ51092.1 | ECTPHS_03312 | ECTPHS_00285 | Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase; COG2030 Acyl dehydratase. | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.985 |
| EHQ51693.1 | EHQ51685.1 | ECTPHS_03312 | ECTPHS_03272 | Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase; COG2030 Acyl dehydratase. | COG0281 Malic enzyme; Belongs to the malic enzymes family. | 0.899 |