Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKT36164.13-methyl-2-oxobutanoate dehydrogenase. (402 aa)    
Predicted Functional Partners:
AKT39977.1
Pyruvate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 0.999
bkdA2
2-oxoisovalerate dehydrogenase subunit beta.
 0.999
AKT42444.1
Branched-chain alpha-keto acid dehydrogenase subunit E2.
 
 0.993
AKT39976.1
Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase.
 
 0.992
lpdA
Dihydrolipoamide dehydrogenase.
 
 
 0.987
maeB
Malic enzyme.
  
 
 0.963
AKT42752.1
Diapophytoene dehydrogenase.
 
 0.931
pdhA
Pyruvate dehydrogenase E1 subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
  
 
0.921
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.917
AKT43269.1
Uncharacterized protein.
  
 
 0.915
Your Current Organism:
Chondromyces crocatus
NCBI taxonomy Id: 52
Other names: C. crocatus, DSM 14714, JCM 12616, Myxobotrys variabilis, TC 601, strain Cm c5
Server load: low (40%) [HD]