STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
leuA2-isopropylmalate synthase. (440 aa)    
Predicted Functional Partners:
AKT36231.1
3-isopropylmalate dehydratase.
 
 0.998
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
 0.990
ilvE-2
Branched-chain amino acid aminotransferase.
 
 0.975
AKT42219.1
Uncharacterized protein; Belongs to the TPP enzyme family.
 
 
 0.969
leuB
3-isopropylmalate dehydrogenase.
 
 0.958
ilvH
Acetolactate synthase; Belongs to the TPP enzyme family.
 
 
 0.954
AKT39797.1
Biotin carboxylase.
  
 
 0.953
AKT40476.1
acetyl-CoA carboxylase.
  
 
 0.953
AKT40946.1
acetyl-CoA carboxylase biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 
 0.953
AKT40949.1
3-isopropylmalate dehydratase large subunit.
 
 
 0.931
Your Current Organism:
Chondromyces crocatus
NCBI taxonomy Id: 52
Other names: C. crocatus, DSM 14714, JCM 12616, Myxobotrys variabilis, TC 601, strain Cm c5
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