STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trxA-2Thioredoxin; Belongs to the thioredoxin family. (107 aa)    
Predicted Functional Partners:
AKT36311.1
Thioredoxin reductase.
 
 
 0.911
AKT41786.1
Thioredoxin reductase.
  
 
 0.870
cysH
Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite.
    
 
 0.773
gap
Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 
 0.758
AKT40266.1
Uncharacterized protein.
  
 
 0.736
trxA
Thioredoxin.
 
 
 0.721
AKT35896.1
Fur family transcriptional regulator; Belongs to the Fur family.
  
 
 0.704
AKT38683.1
Uncharacterized protein; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
 
 0.692
AKT43632.1
Glutamate synthase.
   
 
 0.654
grpE
Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]
 
  
 0.651
Your Current Organism:
Chondromyces crocatus
NCBI taxonomy Id: 52
Other names: C. crocatus, DSM 14714, JCM 12616, Myxobotrys variabilis, TC 601, strain Cm c5
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