Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
aroKTranscriptional regulator; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (310 aa)    
Predicted Functional Partners:
AKT38430.1
Crotonase.
 
   
 0.922
AKT38431.1
benzoyl-CoA oxygenase.
 
   
 0.904
aroB-2
3-dehydroquinate synthase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
 
  
 0.900
AKT38432.1
benzoyl-CoA oxygenase.
 
   
 0.878
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
  
 
 0.835
aldA-3
Aldehyde dehydrogenase.
 
  
 0.824
AKT38426.1
4-hydroxybenzoate--CoA ligase.
 
 
 
 0.808
AKT42223.1
Uncharacterized protein.
 
  
 0.754
AKT42082.1
Alpha/beta hydrolase.
 
  
 0.733
AKT42333.1
Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
 
 
 0.686
Your Current Organism:
Chondromyces crocatus
NCBI taxonomy Id: 52
Other names: C. crocatus, DSM 14714, JCM 12616, Myxobotrys variabilis, TC 601, strain Cm c5
Server load: medium (66%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.