Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fis-8Fis family transcriptional regulator. (187 aa)    
Predicted Functional Partners:
AKT37679.1
Uncharacterized protein.
  
     0.682
AKT36792.1
Uncharacterized protein; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
  
     0.654
AKT42856.1
Uncharacterized protein.
  
    0.588
gst-18
Glutathione S-transferase; Belongs to the GST superfamily.
  
     0.579
AKT43981.1
Uncharacterized protein.
  
    0.542
AKT36756.1
Uncharacterized protein.
 
     0.518
AKT42832.1
Uncharacterized protein.
  
     0.514
AKT36017.1
ABC transporter permease; Belongs to the binding-protein-dependent transport system permease family.
   
   0.485
AKT40014.1
Uncharacterized protein.
  
    0.465
AKT37563.1
Hydrolase.
  
    0.463
Your Current Organism:
Chondromyces crocatus
NCBI taxonomy Id: 52
Other names: C. crocatus, DSM 14714, JCM 12616, Myxobotrys variabilis, TC 601, strain Cm c5
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