Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKT38582.12-keto-4-pentenoate hydratase. (325 aa)    
Predicted Functional Partners:
AKT38581.1
Maleylacetoacetate isomerase.
  
 0.988
hmgA
Homogentisate 1,2-dioxygenase.
 
  
 0.914
hppD
4-hydroxyphenylpyruvate dioxygenase.
 
  
 0.884
fumC
Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.827
AKT36289.1
Succinate dehydrogenase flavoprotein subunit.
  
 
  0.823
sdhA-3
Succinate dehydrogenase.
  
 
  0.823
sdhB
Succinate dehydrogenase iron-sulfur subunit.
  
 
  0.812
sdhA-2
Succinate dehydrogenase.
  
 
  0.812
sdhA-4
Succinate dehydrogenase.
    
  0.808
fumC-2
Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
 0.808
Your Current Organism:
Chondromyces crocatus
NCBI taxonomy Id: 52
Other names: C. crocatus, DSM 14714, JCM 12616, Myxobotrys variabilis, TC 601, strain Cm c5
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