Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKT40592.1Uncharacterized protein. (292 aa)    
Predicted Functional Partners:
AKT40599.1
Uncharacterized protein.
     0.982
maeB
Malic enzyme.
  
 
 0.927
AKT38032.1
Uncharacterized protein.
  
  
 
0.919
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
    
 0.912
lldD
Lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 0.910
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.
     
 0.908
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.908
pckA
Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
     
 0.908
AKT36164.1
3-methyl-2-oxobutanoate dehydrogenase.
    
 0.907
AKT39977.1
Pyruvate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
    
 0.907
Your Current Organism:
Chondromyces crocatus
NCBI taxonomy Id: 52
Other names: C. crocatus, DSM 14714, JCM 12616, Myxobotrys variabilis, TC 601, strain Cm c5
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