STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
malRHTH-type transcriptional regulator MalR. (335 aa)    
Predicted Functional Partners:
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
 
 0.735
crh
HPr-like protein Crh.
   
 
 0.690
ptsH
Phosphocarrier protein HPr.
   
 
 0.690
malE_1
Maltose-binding periplasmic protein.
 
  
 0.636
ribBA
Riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
   0.623
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
    
   0.623
tsaA
Putative peroxiredoxin.
   
   0.596
KXG78102.1
Oligosaccharide 4-alpha-D-glucosyltransferase; Belongs to the glycosyl hydrolase 31 family.
 
  
  0.584
codY
GTP-sensing transcriptional pleiotropic repressor CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family.
    
 
 0.530
malF
Maltose transport system permease protein MalF.
  
  
 0.529
Your Current Organism:
Thermotalea metallivorans
NCBI taxonomy Id: 520762
Other names: Clostridiaceae bacterium B2-1, DSM 21119, JCM 15105, KCTC 5625, T. metallivorans, Thermotalea metallivorans Ogg and Patel 2009, strain B2-1
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