node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
argR | pheT | AN619_08040 | AN619_23660 | Arginine repressor; Regulates arginine biosynthesis genes. | Phenylalanine--tRNA ligase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.612 |
argR | recN | AN619_08040 | AN619_08050 | Arginine repressor; Regulates arginine biosynthesis genes. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.876 |
argR | spoIVB | AN619_08040 | AN619_08060 | Arginine repressor; Regulates arginine biosynthesis genes. | SpoIVB peptidase. | 0.654 |
cinA | cphA | AN619_15660 | AN619_17070 | Putative competence-damage inducible protein; Belongs to the CinA family. | Cyanophycin synthetase; Belongs to the MurCDEF family. | 0.410 |
cinA | lexA | AN619_15660 | AN619_08640 | Putative competence-damage inducible protein; Belongs to the CinA family. | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.694 |
cinA | recA | AN619_15660 | AN619_15670 | Putative competence-damage inducible protein; Belongs to the CinA family. | Hypothetical protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.939 |
cinA | recN | AN619_15660 | AN619_08050 | Putative competence-damage inducible protein; Belongs to the CinA family. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.718 |
cinA | ruvA | AN619_15660 | AN619_05460 | Putative competence-damage inducible protein; Belongs to the CinA family. | Holliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.506 |
cinA | topA | AN619_15660 | AN619_14910 | Putative competence-damage inducible protein; Belongs to the CinA family. | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.426 |
cphA | cinA | AN619_17070 | AN619_15660 | Cyanophycin synthetase; Belongs to the MurCDEF family. | Putative competence-damage inducible protein; Belongs to the CinA family. | 0.410 |
cphA | pheT | AN619_17070 | AN619_23660 | Cyanophycin synthetase; Belongs to the MurCDEF family. | Phenylalanine--tRNA ligase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.807 |
cphA | recA | AN619_17070 | AN619_15670 | Cyanophycin synthetase; Belongs to the MurCDEF family. | Hypothetical protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.493 |
cphA | recN | AN619_17070 | AN619_08050 | Cyanophycin synthetase; Belongs to the MurCDEF family. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.608 |
cphA | ruvA | AN619_17070 | AN619_05460 | Cyanophycin synthetase; Belongs to the MurCDEF family. | Holliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.413 |
cphA | topA | AN619_17070 | AN619_14910 | Cyanophycin synthetase; Belongs to the MurCDEF family. | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.605 |
lexA | cinA | AN619_08640 | AN619_15660 | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | Putative competence-damage inducible protein; Belongs to the CinA family. | 0.694 |
lexA | recA | AN619_08640 | AN619_15670 | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | Hypothetical protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.993 |
lexA | recN | AN619_08640 | AN619_08050 | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.711 |
lexA | topA | AN619_08640 | AN619_14910 | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.460 |
pheT | argR | AN619_23660 | AN619_08040 | Phenylalanine--tRNA ligase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | Arginine repressor; Regulates arginine biosynthesis genes. | 0.612 |