node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
carA | carB | AN619_18610 | AN619_18620 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Carbamoyl-phosphate synthase large chain. | 0.999 |
carA | lhyD | AN619_18610 | AN619_19360 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | L-hydantoinase. | 0.974 |
carA | pyrB | AN619_18610 | AN619_24850 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Aspartate carbamoyltransferase catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
carA | pyrC_2 | AN619_18610 | AN619_24860 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.996 |
carA | pyrD | AN619_18610 | AN619_24890 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. | 0.942 |
carA | pyrE | AN619_18610 | AN619_01820 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.939 |
carA | pyrF | AN619_18610 | AN619_24870 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.903 |
carA | pyrI | AN619_18610 | AN619_24840 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Aspartate carbamoyltransferase regulatory chain. | 0.955 |
carA | pyrK | AN619_18610 | AN619_24880 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). | 0.904 |
carA | pyrR | AN619_18610 | AN619_14380 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Bifunctional protein PyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | 0.888 |
carB | carA | AN619_18620 | AN619_18610 | Carbamoyl-phosphate synthase large chain. | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | 0.999 |
carB | lhyD | AN619_18620 | AN619_19360 | Carbamoyl-phosphate synthase large chain. | L-hydantoinase. | 0.987 |
carB | pyrB | AN619_18620 | AN619_24850 | Carbamoyl-phosphate synthase large chain. | Aspartate carbamoyltransferase catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
carB | pyrC_2 | AN619_18620 | AN619_24860 | Carbamoyl-phosphate synthase large chain. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.996 |
carB | pyrD | AN619_18620 | AN619_24890 | Carbamoyl-phosphate synthase large chain. | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. | 0.987 |
carB | pyrE | AN619_18620 | AN619_01820 | Carbamoyl-phosphate synthase large chain. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.966 |
carB | pyrF | AN619_18620 | AN619_24870 | Carbamoyl-phosphate synthase large chain. | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.977 |
carB | pyrI | AN619_18620 | AN619_24840 | Carbamoyl-phosphate synthase large chain. | Aspartate carbamoyltransferase regulatory chain. | 0.947 |
carB | pyrK | AN619_18620 | AN619_24880 | Carbamoyl-phosphate synthase large chain. | Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). | 0.959 |
carB | pyrR | AN619_18620 | AN619_14380 | Carbamoyl-phosphate synthase large chain. | Bifunctional protein PyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | 0.937 |