STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sigERNA polymerase sigma-35 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (239 aa)    
Predicted Functional Partners:
spoIIGA
Sporulation sigma-E factor-processing peptidase; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family.
 
  
 0.953
KXG78468.1
Hypothetical protein.
 
     0.890
spo0A
Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.860
KXG75212.1
Hypothetical protein.
 
     0.805
spoIIID
Stage III sporulation protein D.
  
    0.804
spoVT
Stage V sporulation protein T.
  
    0.804
spoIVA
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
    0.782
KXG78132.1
Hypothetical protein.
  
     0.775
spoVAD
Stage V sporulation protein AD.
  
     0.775
KXG78134.1
Hypothetical protein.
  
     0.775
Your Current Organism:
Fervidicola ferrireducens
NCBI taxonomy Id: 520764
Other names: DSM 21121, F. ferrireducens, Fervidicola ferrireducens Ogg and Patel 2009, JCM 15106, KCTC 5610, Thermoanaerobacteriaceae bacterium Y170, strain Y170
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.