STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (296 aa)    
Predicted Functional Partners:
hom
Homoserine dehydrogenase.
 
 0.999
thrC
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
 
 
 0.999
metH_3
Methionine synthase.
    
 0.933
ask
Aspartokinase; Belongs to the aspartokinase family.
 
 0.919
purM
Phosphoribosylformylglycinamidine cyclo-ligase.
 
    
 0.911
ilvE
Branched-chain-amino-acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.897
cysE
Serine acetyltransferase.
     
 0.891
sdhA
L-serine dehydratase, alpha chain; Belongs to the iron-sulfur dependent L-serine dehydratase family.
  
 
 0.889
sdhB
L-serine dehydratase, beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family.
  
 
 0.889
mdeA_2
Methionine gamma-lyase.
    
  0.877
Your Current Organism:
Fervidicola ferrireducens
NCBI taxonomy Id: 520764
Other names: DSM 21121, F. ferrireducens, Fervidicola ferrireducens Ogg and Patel 2009, JCM 15106, KCTC 5610, Thermoanaerobacteriaceae bacterium Y170, strain Y170
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.