node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cdr | glyA | AN618_16900 | AN618_07380 | Coenzyme A disulfide reductase; Belongs to the sulfur carrier protein TusA family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.932 |
cdr | hcnA | AN618_16900 | AN618_17220 | Coenzyme A disulfide reductase; Belongs to the sulfur carrier protein TusA family. | Hydrogen cyanide synthase subunit HcnA. | 0.807 |
cdr | hcnB_1 | AN618_16900 | AN618_17230 | Coenzyme A disulfide reductase; Belongs to the sulfur carrier protein TusA family. | Hydrogen cyanide synthase subunit HcnB. | 0.918 |
cdr | hcnB_2 | AN618_16900 | AN618_17250 | Coenzyme A disulfide reductase; Belongs to the sulfur carrier protein TusA family. | Hydrogen cyanide synthase subunit HcnB. | 0.412 |
cdr | ltaA | AN618_16900 | AN618_23020 | Coenzyme A disulfide reductase; Belongs to the sulfur carrier protein TusA family. | L-allo-threonine aldolase. | 0.531 |
cdr | metH_3 | AN618_16900 | AN618_10540 | Coenzyme A disulfide reductase; Belongs to the sulfur carrier protein TusA family. | Methionine synthase. | 0.887 |
cdr | sfrB | AN618_16900 | AN618_08910 | Coenzyme A disulfide reductase; Belongs to the sulfur carrier protein TusA family. | NADPH-Fe(3+) oxidoreductase subunit beta. | 0.997 |
cdr | soxB | AN618_16900 | AN618_17260 | Coenzyme A disulfide reductase; Belongs to the sulfur carrier protein TusA family. | Sarcosine oxidase subunit beta. | 0.989 |
cdr | trxB_1 | AN618_16900 | AN618_13440 | Coenzyme A disulfide reductase; Belongs to the sulfur carrier protein TusA family. | Thioredoxin reductase. | 0.922 |
glyA | cdr | AN618_07380 | AN618_16900 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Coenzyme A disulfide reductase; Belongs to the sulfur carrier protein TusA family. | 0.932 |
glyA | hcnB_1 | AN618_07380 | AN618_17230 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Hydrogen cyanide synthase subunit HcnB. | 0.692 |
glyA | ltaA | AN618_07380 | AN618_23020 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | L-allo-threonine aldolase. | 0.925 |
glyA | metH_3 | AN618_07380 | AN618_10540 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Methionine synthase. | 0.927 |
glyA | sfrB | AN618_07380 | AN618_08910 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | NADPH-Fe(3+) oxidoreductase subunit beta. | 0.861 |
glyA | soxB | AN618_07380 | AN618_17260 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Sarcosine oxidase subunit beta. | 0.804 |
glyA | trxB_1 | AN618_07380 | AN618_13440 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Thioredoxin reductase. | 0.692 |
hcnA | cdr | AN618_17220 | AN618_16900 | Hydrogen cyanide synthase subunit HcnA. | Coenzyme A disulfide reductase; Belongs to the sulfur carrier protein TusA family. | 0.807 |
hcnA | hcnB_1 | AN618_17220 | AN618_17230 | Hydrogen cyanide synthase subunit HcnA. | Hydrogen cyanide synthase subunit HcnB. | 0.996 |
hcnA | hcnB_2 | AN618_17220 | AN618_17250 | Hydrogen cyanide synthase subunit HcnA. | Hydrogen cyanide synthase subunit HcnB. | 0.961 |
hcnA | rsxB_4 | AN618_17220 | AN618_17240 | Hydrogen cyanide synthase subunit HcnA. | Electron transport complex subunit RsxB. | 0.988 |