node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cysE | glyA | AN618_20530 | AN618_07380 | Serine acetyltransferase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.891 |
cysE | hom | AN618_20530 | AN618_06400 | Serine acetyltransferase. | Homoserine dehydrogenase. | 0.883 |
cysE | ppaT | AN618_20530 | AN618_13950 | Serine acetyltransferase. | Pyridoxamine--pyruvate transaminase. | 0.677 |
cysE | sdhA | AN618_20530 | AN618_20080 | Serine acetyltransferase. | L-serine dehydratase, alpha chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.880 |
cysE | sdhB | AN618_20530 | AN618_20090 | Serine acetyltransferase. | L-serine dehydratase, beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.880 |
cysE | tdcB_1 | AN618_20530 | AN618_03000 | Serine acetyltransferase. | L-threonine dehydratase catabolic TdcB. | 0.760 |
cysE | tdcB_2 | AN618_20530 | AN618_20100 | Serine acetyltransferase. | L-threonine ammonia-lyase. | 0.787 |
cysE | thrB | AN618_20530 | AN618_06420 | Serine acetyltransferase. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.891 |
dctA | sdhA | AN618_20070 | AN618_20080 | C4-dicarboxylate transport protein; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. | L-serine dehydratase, alpha chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.755 |
dctA | sdhB | AN618_20070 | AN618_20090 | C4-dicarboxylate transport protein; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. | L-serine dehydratase, beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.745 |
dctA | tdcB_2 | AN618_20070 | AN618_20100 | C4-dicarboxylate transport protein; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. | L-threonine ammonia-lyase. | 0.622 |
glyA | cysE | AN618_07380 | AN618_20530 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Serine acetyltransferase. | 0.891 |
glyA | hom | AN618_07380 | AN618_06400 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Homoserine dehydrogenase. | 0.561 |
glyA | ppaT | AN618_07380 | AN618_13950 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Pyridoxamine--pyruvate transaminase. | 0.745 |
glyA | pspA | AN618_07380 | AN618_19120 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phosphoserine phosphatase 1; Belongs to the phosphoglycerate mutase family. | 0.898 |
glyA | sdhA | AN618_07380 | AN618_20080 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | L-serine dehydratase, alpha chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.949 |
glyA | sdhB | AN618_07380 | AN618_20090 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | L-serine dehydratase, beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.951 |
glyA | tdcB_1 | AN618_07380 | AN618_03000 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | L-threonine dehydratase catabolic TdcB. | 0.786 |
glyA | tdcB_2 | AN618_07380 | AN618_20100 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | L-threonine ammonia-lyase. | 0.863 |
hom | cysE | AN618_06400 | AN618_20530 | Homoserine dehydrogenase. | Serine acetyltransferase. | 0.883 |