STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ldh_1Leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (346 aa)    
Predicted Functional Partners:
sfrB
NADPH-Fe(3+) oxidoreductase subunit beta.
  
 0.953
buk2_1
Butyrate kinase 2; Belongs to the acetokinase family.
  
  
 0.921
gltB_2
Glutamate synthase [NADPH] large chain; Belongs to the glutamate synthase family.
  
 0.870
KYO68085.1
Hypothetical protein.
  
 0.870
pta_1
Phosphate acetyltransferase.
  
  
 0.870
ilvE
Branched-chain-amino-acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.848
acoA
Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha.
  
 
 0.835
bfmBAB
2-oxoisovalerate dehydrogenase subunit beta.
  
 
 0.821
cobB
NAD-dependent protein deacetylase.
   
 0.785
korA_1
2-oxoglutarate oxidoreductase subunit KorA.
    
 0.750
Your Current Organism:
Thermovenabulum gondwanense
NCBI taxonomy Id: 520767
Other names: DSM 21133, KCTC 5616, T. gondwanense, Thermovenabulum gondwanense Ogg et al. 2010 emend. Pradel et al. 2013, Thermovenabulum sp. R270, strain R270
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