STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pbpBPenicillin-binding protein PbpB. (511 aa)    
Predicted Functional Partners:
rodA
Putative FtsW-like protein; Belongs to the SEDS family.
 
 0.988
mrdB
Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
 
 0.981
ftsW
Putative lipid II flippase FtsW; Belongs to the SEDS family.
 
 0.978
mrdA
Penicillin-binding protein 2.
  
  
0.888
KYO66684.1
Hypothetical protein; Essential cell division protein.
  
 
 0.881
mreC
Cell shape-determining protein MreC; Involved in formation and maintenance of cell shape.
 
 
 0.827
pbpF
Penicillin-binding protein 1F.
 
 
0.820
murE
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
  
 0.769
spoVD
Stage V sporulation protein D.
 
  
0.750
mreB_2
Rod shape-determining protein MreB.
 
 
 0.694
Your Current Organism:
Thermovenabulum gondwanense
NCBI taxonomy Id: 520767
Other names: DSM 21133, KCTC 5616, T. gondwanense, Thermovenabulum gondwanense Ogg et al. 2010 emend. Pradel et al. 2013, Thermovenabulum sp. R270, strain R270
Server load: low (18%) [HD]