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hpt protein (Methanosphaerula palustris) - STRING interaction network
"hpt" - Hypoxanthine/guanine phosphoribosyltransferase in Methanosphaerula palustris
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
hptHypoxanthine/guanine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis; Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily (182 aa)    
Predicted Functional Partners:
Mpal_1701
TIGRFAM- adenylosuccinate lyase; PFAM- fumarate lyase; KEGG- mem-Memar_0781 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily (445 aa)
   
  0.976
guaAB
GMP synthase [glutamine-hydrolyzing] subunit B; Catalyzes the synthesis of GMP from XMP (305 aa)
   
  0.971
Mpal_2083
Methyltransferase small; PFAM- putative RNA methylase; methyltransferase small; Methyltransferase type 11; KEGG- mem-Memar_1845 methyltransferase small (204 aa)
 
          0.968
Mpal_2079
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family (761 aa)
         
  0.966
ade
KEGG- mbn-Mboo_1575 adenine deaminase; TIGRFAM- adenine deaminase; PFAM- amidohydrolase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family (567 aa)
       
  0.964
Mpal_2082
TIGRFAM- diphthamide biosynthesis protein; PFAM- Diphthamide synthesis DPH2 protein; KEGG- mem-Memar_1846 diphthamide biosynthesis protein (315 aa)
              0.962
mfnA
Probable L-tyrosine/L-aspartate decarboxylase; Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis; Belongs to the group II decarboxylase family. MfnA subfamily (363 aa)
         
  0.961
Mpal_2351
KEGG- mbn-Mboo_1205 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM- phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM- MGS domain protein; AICARFT/IMPCHase bienzyme formylation region (496 aa)
 
 
  0.955
Mpal_1085
PFAM- PfkB domain protein; KEGG- mbn-Mboo_1658 ribokinase-like domain-containing protein; Belongs to the carbohydrate kinase PfkB family (294 aa)
   
  0.950
guaAA
GMP synthase [glutamine-hydrolyzing] subunit A; Catalyzes the synthesis of GMP from XMP (185 aa)
   
 
  0.933
Your Current Organism:
Methanosphaerula palustris
NCBI taxonomy Id: 521011
Other names: Candidatus Methanosphaerula palustris E1-9c, M. palustris E1-9c, Methanosphaerula palustris, Methanosphaerula palustris E1-9c, Methanosphaerula palustris str. E1-9c, Methanosphaerula palustris strain E1-9c
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