SDE42892.1 protein (Limimaricola pyoseonensis)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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[Homology]

Score

SDE42892.1

Protein of unknown function. (92 aa)

Predicted Functional Partners:

SDE42861.1

0.874

SDE42921.1

0.708

SDE82669.1

0.705

SDF10898.1

0.606

SDE11089.1

0.604

SDE35099.1

0.594

SDE50401.1

0.566

SDE93728.1

0.566

SDE42802.1

0.542

SDE42833.1

0.542

Your Current Organism:

Limimaricola pyoseonensis

NCBI taxonomy Id: 521013
Other names: DSM 21424, KCTC 22372, L. pyoseonensis, Loktanella pyoseonensis, Loktanella pyoseonensis Moon et al. 2010, strain JJM85

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SDE11089.1	SDE35099.1	SAMN04488567_0858	SAMN04488567_1382	Hypothetical protein.	Membrane associated serine protease, rhomboid family.	0.752
SDE11089.1	SDE42892.1	SAMN04488567_0858	SAMN04488567_1647	Hypothetical protein.	Protein of unknown function.	0.604
SDE11089.1	SDE50401.1	SAMN04488567_0858	SAMN04488567_1923	Hypothetical protein.	Hypothetical protein.	0.715
SDE11089.1	SDE82669.1	SAMN04488567_0858	SAMN04488567_2701	Hypothetical protein.	SseB protein N-terminal domain-containing protein.	0.732
SDE11089.1	SDE93728.1	SAMN04488567_0858	SAMN04488567_3008	Hypothetical protein.	Protein of unknown function.	0.524
SDE11089.1	SDF10898.1	SAMN04488567_0858	SAMN04488567_3427	Hypothetical protein.	Protein of unknown function.	0.436
SDE35099.1	SDE11089.1	SAMN04488567_1382	SAMN04488567_0858	Membrane associated serine protease, rhomboid family.	Hypothetical protein.	0.752
SDE35099.1	SDE42892.1	SAMN04488567_1382	SAMN04488567_1647	Membrane associated serine protease, rhomboid family.	Protein of unknown function.	0.594
SDE35099.1	SDE50401.1	SAMN04488567_1382	SAMN04488567_1923	Membrane associated serine protease, rhomboid family.	Hypothetical protein.	0.764
SDE35099.1	SDE82669.1	SAMN04488567_1382	SAMN04488567_2701	Membrane associated serine protease, rhomboid family.	SseB protein N-terminal domain-containing protein.	0.761
SDE35099.1	SDE93728.1	SAMN04488567_1382	SAMN04488567_3008	Membrane associated serine protease, rhomboid family.	Protein of unknown function.	0.724
SDE35099.1	SDF10898.1	SAMN04488567_1382	SAMN04488567_3427	Membrane associated serine protease, rhomboid family.	Protein of unknown function.	0.438
SDE42802.1	SDE42833.1	SAMN04488567_1644	SAMN04488567_1645	NUDIX domain-containing protein.	Uncharacterized conserved protein, DUF983 family; Manually curated.	0.885
SDE42802.1	SDE42861.1	SAMN04488567_1644	SAMN04488567_1646	NUDIX domain-containing protein.	Phosphoglycolate phosphatase.	0.542
SDE42802.1	SDE42892.1	SAMN04488567_1644	SAMN04488567_1647	NUDIX domain-containing protein.	Protein of unknown function.	0.542
SDE42802.1	SDE42921.1	SAMN04488567_1644	SAMN04488567_1648	NUDIX domain-containing protein.	Response regulator receiver modulated diguanylate cyclase.	0.489
SDE42833.1	SDE42802.1	SAMN04488567_1645	SAMN04488567_1644	Uncharacterized conserved protein, DUF983 family; Manually curated.	NUDIX domain-containing protein.	0.885
SDE42833.1	SDE42861.1	SAMN04488567_1645	SAMN04488567_1646	Uncharacterized conserved protein, DUF983 family; Manually curated.	Phosphoglycolate phosphatase.	0.542
SDE42833.1	SDE42892.1	SAMN04488567_1645	SAMN04488567_1647	Uncharacterized conserved protein, DUF983 family; Manually curated.	Protein of unknown function.	0.542
SDE42833.1	SDE42921.1	SAMN04488567_1645	SAMN04488567_1648	Uncharacterized conserved protein, DUF983 family; Manually curated.	Response regulator receiver modulated diguanylate cyclase.	0.401

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Network Stats

number of nodes:

11

number of edges:

53

average node degree:

9.64

avg. local clustering coefficient:

0.968

expected number of edges:

11

PPI enrichment p-value:

< 1.0e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006563

L-serine metabolic process

3 of 6

2.35

2.18

7.21e-05

GO:0008652

Cellular amino acid biosynthetic process

7 of 104

1.48

2.05

8.24e-07

GO:0009070

Serine family amino acid biosynthetic process

3 of 13

2.02

1.69

0.00044

GO:0000105

Histidine biosynthetic process

3 of 13

2.02

1.69

0.00044

GO:0006564

L-serine biosynthetic process

2 of 2

2.65

1.52

0.0017

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004636

phosphoribosyl-ATP diphosphatase activity

2 of 2

2.65

0.97

0.0175

GO:0004635

phosphoribosyl-AMP cyclohydrolase activity

2 of 2

2.65

0.97

0.0175

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

10 of 1378

0.52

0.4

0.0029

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1258

Biosynthesis of amino acids

8 of 75

1.68

3.14

7.50e-10

CL:1260

Cysteine and methionine metabolism

5 of 28

1.91

2.62

1.56e-06

CL:1390

Histidine biosynthesis

3 of 5

2.43

2.13

9.98e-05

CL:1306

Serine biosynthesis, and Organic phosphonate metabolic process

3 of 5

2.43

2.13

9.98e-05

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00260

Glycine, serine and threonine metabolism

7 of 46

1.84

3.69

2.11e-10

map01230

Biosynthesis of amino acids

10 of 141

1.51

3.02

6.73e-13

map00680

Methane metabolism

5 of 28

1.91

3.0

1.34e-07

map00270

Cysteine and methionine metabolism

5 of 39

1.76

2.6

4.86e-07

map00340

Histidine metabolism

3 of 24

1.75

1.6

0.00037

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0028

Amino-acid biosynthesis

6 of 54

1.7

2.59

2.14e-07

KW-0368

Histidine biosynthesis

3 of 10

2.13

1.87

0.00023

KW-0718

Serine biosynthesis

2 of 2

2.65

1.5

0.0018

KW-0032

Aminotransferase

2 of 17

1.73

0.73

0.0379

KW-0963

Cytoplasm

4 of 222

0.91

0.49

0.0433

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