STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Kole_0022PFAM: surface antigen variable number repeat protein; surface antigen (D15); KEGG: tcx:Tcr_1278 surface antigen (D15). (836 aa)    
Predicted Functional Partners:
Kole_1437
PFAM: Fibronectin type III domain protein; SMART: Fibronectin type III domain protein; KEGG: mmr:Mmar10_1504 cadherin.
 
 
 0.909
Kole_0023
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: dat:HRM2_16530 sensory signal transduction histidine kinase (ATPase domain protein).
   
   0.799
Kole_0024
PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: dat:HRM2_16540 metal-dependent phosphoesterase (PHP family protein).
       0.790
Kole_0025
KEGG: dat:HRM2_16550 iron-sulfur binding hydrogenase.
       0.790
Kole_1650
Putative transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; KEGG: hypothetical protein.
 
  
 0.760
Kole_0026
Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; ATP-binding region ATPase domain protein; SMART: CBS domain containing protein; KEGG: dat:HRM2_16560 RsbW2.
       0.754
Kole_0980
KEGG: sus:Acid_0995 hypothetical protein.
  
     0.744
Kole_1472
Hypothetical protein; KEGG: gur:Gura_0070 APHP domain-containing protein.
  
   
 0.744
Kole_1519
PFAM: O-antigen polymerase; KEGG: vfm:VFMJ11_A1152 secreted polysaccharide polymerase.
 
     0.744
Kole_1776
Hypothetical protein; KEGG: psa:PST_4209 probable NADH dehydrogenase.
  
     0.738
Your Current Organism:
Kosmotoga olearia
NCBI taxonomy Id: 521045
Other names: K. olearia TBF 19.5.1, Kosmotoga olearia TBF 19.5.1, Thermotogales bacterium TBF 19.5.1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.