STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Kole_0443KEGG: sfu:Sfum_4032 putative anti-sigma regulatory factor, serine/threonine protein kinase. (134 aa)    
Predicted Functional Partners:
Kole_0441
PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: esa:ESA_01838 hypothetical protein.
  
 
 0.963
Kole_0442
PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: bha:BH1536 anti-sigma F factor antagonist (stage II sporulation protein AA).
  
 
 0.963
Kole_0444
Hpt sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: response regulator receiver; histidine kinase A domain protein; ATP-binding region ATPase domain protein; KEGG: nis:NIS_1346 two-component sensor histidine kinase/response regulator.
 
  
 0.910
Kole_0440
PFAM: response regulator receiver; Stage II sporulation E family protein; SMART: response regulator receiver; protein phosphatase 2C domain protein; KEGG: sat:SYN_00230 response regulator receiver domain-containing protein.
 
 
 0.902
Kole_1792
PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: pca:Pcar_0518 hypothetical protein.
  
 
 0.682
Kole_0452
KEGG: gur:Gura_2803 metal dependent phosphohydrolase; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; GAF domain protein; metal-dependent phosphohydrolase HD sub domain; PAS fold-4 domain protein; SMART: GGDEF domain containing protein; metal-dependent phosphohydrolase HD region; GAF domain protein.
  
 
 0.681
Kole_0660
KEGG: afr:AFE_1707 sensory box-containing diguanylate cyclase, putative; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold domain protein; PAS fold-4 domain protein; SMART: GGDEF domain containing protein; PAC repeat-containing protein; PAS domain containing protein.
  
 
 0.637
Kole_0394
PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; KEGG: dps:DP2377 thiamine biosynthesis protein ThiH.
   
    0.616
Kole_0439
PFAM: protein of unknown function DUF214; KEGG: gbm:Gbem_2168 protein of unknown function DUF214.
       0.566
Kole_0436
Hypothetical protein.
       0.564
Your Current Organism:
Kosmotoga olearia
NCBI taxonomy Id: 521045
Other names: K. olearia TBF 19.5.1, Kosmotoga olearia TBF 19.5.1, Thermotogales bacterium TBF 19.5.1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.