close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Kole_1007PFAM: protein of unknown function DUF218; KEGG: nmu:Nmul_A0343 hypothetical protein. (254 aa)    
Predicted Functional Partners:
Kole_1008
PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: nis:NIS_0508 glycerophosphoryl diester phosphodiesterase.
       0.784
Kole_1006
KEGG: pap:PSPA7_5383 hypothetical protein.
       0.773
Kole_1009
Hypothetical protein.
       0.768
Kole_0012
PFAM: polysaccharide export protein; KEGG: ppr:PBPRA0349 putative periplasmic protein involved in polysaccharide export.
 
    0.520
Your Current Organism:
Kosmotoga olearia
NCBI taxonomy Id: 521045
Other names: K. olearia TBF 19.5.1, Kosmotoga olearia TBF 19.5.1, Thermotogales bacterium TBF 19.5.1
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.