STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Apar_0295PFAM: Silent information regulator protein Sir2; KEGG: cvi:CV_0294 NAD-dependent deacetylase. (283 aa)    
Predicted Functional Partners:
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 0.939
Apar_0896
Amidohydrolase-like protein; KEGG: afr:AFE_0428 glutamine-dependent NAD+ synthetase.
  
 0.939
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
   
 0.929
Apar_0977
PFAM: protein of unknown function DUF523; purine or other phosphorylase family 1; KEGG: bsu:BSU23490 purine nucleoside phosphorylase.
    
 0.920
Apar_0141
TIGRFAM: purine nucleoside phosphorylase; PFAM: purine or other phosphorylase family 1; KEGG: purine nucleoside phosphorylase; K03784 purine-nucleoside phosphorylase.
    
 0.919
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
 0.919
Apar_0610
Glutamate dehydrogenase (NADP(+)); PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: dds:Ddes_1152 glutamate dehydrogenase (NADP(+)); Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 0.899
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.698
Apar_0519
KEGG: bsu:BSU27620 hypothetical protein; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; DEAD/DEAH box helicase domain protein; helicase domain protein; phosphoesterase DHHA1; SMART: helicase domain protein; DEAD-like helicase.
  
 
 0.596
Apar_1295
TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator; KEGG: bcy:Bcer98_3735 cell envelope-related transcriptional attenuator.
  
    0.589
Your Current Organism:
Atopobium parvulum
NCBI taxonomy Id: 521095
Other names: A. parvulum DSM 20469, Atopobium parvulum ATCC 33793, Atopobium parvulum DSM 20469, Atopobium parvulum JCM 10300, Atopobium parvulum str. DSM 20469, Atopobium parvulum strain DSM 20469
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