STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Apar_0971TIGRFAM: ferrous iron transport protein B; small GTP-binding protein; PFAM: GTP-binding protein HSR1-related; nucleoside recognition domain protein; Ferrous iron transport protein B domain protein; Ferrous iron transport B domain protein; KEGG: ppr:PBPRB1904 ferrous ion transport protein B. (886 aa)    
Predicted Functional Partners:
Apar_0972
PFAM: FeoA family protein; KEGG: ank:AnaeK_3367 FeoA family protein.
 
  
 0.983
Apar_0973
PFAM: FeoA family protein; KEGG: dal:Dalk_1640 ferric uptake regulator, Fur family.
 
  
 0.939
Apar_1328
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: eca:ECA2957 pyruvate-flavodoxin oxidoreductase.
     
 0.534
Apar_0439
TIGRFAM: heavy metal translocating P-type ATPase; copper-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper ion binding protein; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase; KEGG: abu:Abu_0480 heavy-metal transporting P-type ATPase.
  
 
 0.449
topA
DNA topoisomerase type IA central domain protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken s [...]
      
 0.436
Your Current Organism:
Atopobium parvulum
NCBI taxonomy Id: 521095
Other names: A. parvulum DSM 20469, Atopobium parvulum ATCC 33793, Atopobium parvulum DSM 20469, Atopobium parvulum JCM 10300, Atopobium parvulum str. DSM 20469, Atopobium parvulum strain DSM 20469
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