STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Apar_1069TIGRFAM: 1-phosphofructokinase; PFAM: PfkB domain protein; KEGG: bca:BCE_1907 tagatose-6-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. (311 aa)    
Predicted Functional Partners:
Apar_1070
KEGG: spe:Spro_2579 tagatose-bisphosphate aldolase; TIGRFAM: ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II.
 
 
 0.960
Apar_0321
TIGRFAM: PTS system, fructose subfamily, IIC subunit; PTS system, fructose-specific, IIB subunnit; PFAM: phosphotransferase system PTS fructose- specific IIB subunit; phosphotransferase system EIIC; KEGG: stm:STM3255 putative phosphotransferase system fructose-specific component IIB.
 
  
 0.939
Apar_0322
1-phosphofructokinase; KEGG: sek:SSPA2915 possible carbohydrate kinase; TIGRFAM: 1-phosphofructokinase; PFAM: PfkB domain protein.
  
  
 
0.926
pfp
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
     
 0.905
pfp-2
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
     
 0.905
Apar_1307
KEGG: sus:Acid_7018 ribose-5-phosphate isomerase; TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase.
  
  
 0.511
Apar_0600
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
  
  
 0.506
Apar_0078
PFAM: glycoside hydrolase family 1; KEGG: bha:BH3918 beta-glucosidase; Belongs to the glycosyl hydrolase 1 family.
  
  
 0.501
Apar_0081
PFAM: phosphotransferase system PTS lactose/cellobiose-specific IIA subunit; KEGG: bcy:Bcer98_3752 phosphotransferase system PTS lactose/cellobiose-specific IIA subunit.
  
  
 0.498
Apar_0324
Transcriptional regulator, DeoR family; PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; SMART: regulatory protein DeoR; KEGG: hap:HAPS_0195 transcriptional repressor AgaR/DNA-binding transcriptional dual regulator.
  
  
 0.486
Your Current Organism:
Atopobium parvulum
NCBI taxonomy Id: 521095
Other names: A. parvulum DSM 20469, Atopobium parvulum ATCC 33793, Atopobium parvulum DSM 20469, Atopobium parvulum JCM 10300, Atopobium parvulum str. DSM 20469, Atopobium parvulum strain DSM 20469
Server load: medium (66%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.