Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
crgAProtein of unknown function UPF0233; Involved in cell division; Belongs to the CrgA family. (97 aa)    
Predicted Functional Partners:
Tpau_0024
KEGG: sen:SACE_0036 hypothetical protein.
 
   
 0.774
Tpau_2638
KEGG: mkm:Mkms_3310 DivIVA family protein; TIGRFAM: DivIVA domain; PFAM: DivIVA family protein.
  
   
 0.739
Tpau_0026
KEGG: rop:ROP_35100 anthranilate synthase component II; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I.
       0.676
Tpau_2644
Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein.
  
 
 
 0.664
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
    
 
 0.621
Tpau_0029
PFAM: penicillin-binding protein transpeptidase; KEGG: rha:RHA1_ro03698 peptidoglycan glycosyltransferase.
   
 
 0.616
Tpau_2652
KEGG: rha:RHA1_ro01094 peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain.
   
 
 0.585
Tpau_1498
(Glutamate--ammonia-ligase) adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal tra [...]
  
   
 0.581
Tpau_2647
KEGG: rer:RER_35530 cell division protein FtsW; TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; Belongs to the SEDS family.
     
 0.575
Tpau_0028
KEGG: nfa:nfa810 putative serine/threonine protein kinase; PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; SMART: serine/threonine protein kinase; tyrosine protein kinase.
     
 0.553
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.