Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_0040PFAM: regulatory protein TetR; KEGG: sen:SACE_5722 TetR family transcriptional regulator. (195 aa)    
Predicted Functional Partners:
Tpau_2357
Transcriptional regulator, TetR family; PFAM: Tetracyclin repressor domain protein; regulatory protein TetR; KEGG: rha:RHA1_ro02950 TetR family transcriptional regulator.
  
     0.612
Tpau_1662
Transcriptional regulator, TetR family; PFAM: Tetracyclin repressor domain protein; regulatory protein TetR; KEGG: sma:SAV_3379 TetR family transcriptional regulator.
  
     0.576
Tpau_2572
Transcriptional regulator, TetR family; PFAM: regulatory protein TetR; Tetracyclin repressor domain protein; KEGG: ami:Amir_4056 transcriptional regulator, TetR family.
  
     0.526
Tpau_0041
PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: cmi:CMM_0578 putative quinone reductase.
       0.501
Tpau_3462
PFAM: regulatory protein TetR; KEGG: ami:Amir_2879 regulatory protein TetR.
  
     0.483
Tpau_4132
Transcriptional regulator, TetR family; PFAM: regulatory protein TetR; Tetracyclin repressor domain protein; KEGG: nfa:nfa18310 putative transcriptional regulator.
  
     0.468
Tpau_4031
PFAM: Activator of Hsp90 ATPase 1 family protein; Polyketide cyclase/dehydrase; KEGG: rop:ROP_55980 hypothetical protein.
  
     0.429
Tpau_0038
PFAM: flavoprotein; KEGG: fra:Francci3_1816 flavoprotein.
       0.422
Tpau_0037
PFAM: major facilitator superfamily MFS_1; General substrate transporter; KEGG: car:cauri_2115 permease of the major facilitator superfamily.
       0.420
Tpau_0039
KEGG: saq:Sare_3599 XRE family transcriptional regulator; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein.
       0.420
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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