Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_0140PFAM: regulatory protein TetR; KEGG: mmi:MMAR_1611 transcriptional regulatory protein. (192 aa)    
Predicted Functional Partners:
Tpau_0141
PFAM: major facilitator superfamily MFS_1; KEGG: sav:SAVP032 QacA protein.
 
     0.825
Tpau_3750
PFAM: helix-turn-helix HxlR type; KEGG: sen:SACE_6745 MarR family transcriptional regulator.
   
    0.594
Tpau_0136
KEGG: nfa:nfa1290 putative transcriptional regulator; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator.
   
    0.566
Tpau_0139
KEGG: mab:MAB_1432 hypothetical protein.
       0.545
Tpau_0195
KEGG: ach:Achl_0269 transcriptional regulator, ArgP, LysR family; TIGRFAM: transcriptional regulator, ArgP family; PFAM: regulatory protein LysR; LysR substrate- binding.
   
    0.531
cobB
PFAM: Silent information regulator protein Sir2; KEGG: mbt:JTY_1185 NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily.
   
    0.528
cobB-2
Silent information regulator protein Sir2; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class II subfamily.
   
    0.528
Tpau_1466
KEGG: mab:MAB_2776 hypothetical protein.
   
    0.505
Tpau_2510
Putative transcriptional regulator; PFAM: regulatory protein ArsR; Helix-turn-helix type 11 domain protein; KEGG: rer:RER_30540 hypothetical protein.
  
    0.505
Tpau_1519
KEGG: bur:Bcep18194_B3011 AraC family transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain.
   
    0.502
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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