Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pheAKEGG: mjl:Mjls_5415 prephenate dehydratase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein. (311 aa)    
Predicted Functional Partners:
Tpau_4050
PFAM: Prephenate dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; 6- phosphogluconate dehydrogenase NAD-binding; KEGG: rer:RER_03280 prephenate dehydrogenase.
 
 0.978
hisC
KEGG: nfa:nfa18460 histidinol-phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
 
 0.918
Tpau_3314
KEGG: mkm:Mkms_2781 chorismate mutase; TIGRFAM: chorismate mutase; PFAM: Chorismate mutase.
  
 
 0.918
Tpau_3331
Chorismate mutase; KEGG: nfa:nfa49960 hypothetical protein; TIGRFAM: chorismate mutase; PFAM: Chorismate mutase.
  
 
 0.918
pat
Histidinol-phosphate aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.918
katG
Catalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.
     
  0.800
Tpau_0146
PFAM: Phosphoglycerate mutase; KEGG: rer:RER_01880 phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family.
       0.794
Tpau_2863
KEGG: rop:ROP_65400 acetolactate synthase small subunit; TIGRFAM: acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein.
 
  
 0.674
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
 
   
 0.657
serC
Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
  
  
 0.655
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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