Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_0177D-lactate dehydrogenase (cytochrome); KEGG: rer:RER_51320 FAD-linked oxidase; PFAM: FAD linked oxidase domain protein. (449 aa)    
Predicted Functional Partners:
Tpau_1211
2-oxoglutarate dehydrogenase, E1 subunit; KEGG: rha:RHA1_ro06012 alpha-ketoglutarate decarboxylase; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: Transketolase central region; dehydrogenase E1 component; catalytic domain of components of various dehydrogenase complexes.
  
 
 0.922
Tpau_0992
Putative transcriptional regulator, GntR family; PFAM: aminotransferase class I and II; KEGG: nfa:nfa9700 putative aminotransferase.
    
  0.916
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
  
 
 0.915
Tpau_3005
KEGG: rop:ROP_21900 putative 4-hydroxy-2- oxoglutarate/2-dehydro-3-deoxy-phosphogluconate aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase.
   
 
 0.906
Tpau_4209
TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; KEGG: rop:ROP_20810 4-hydroxy-2-oxoglutarate/2- dehydro-3-deoxy-phosphogluconate aldolase; PFAM: KDPG and KHG aldolase.
   
 
 0.906
Tpau_2442
PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sma:SAV_3908 hydrolase.
    
 0.905
Tpau_3668
KEGG: mab:MAB_4095c isocitrate lyase (AceA); TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase.
     
 0.903
Tpau_3499
KEGG: nca:Noca_1780 D-amino-acid oxidase; PFAM: FAD dependent oxidoreductase.
     
 0.803
Tpau_0175
PFAM: Beta-ketoacyl synthase; Acyl transferase; Thioesterase; phosphopantetheine-binding; KEGG: rha:RHA1_ro04065 polyketide synthase.
  
 
 0.782
Tpau_0176
PFAM: carboxyl transferase; KEGG: rha:RHA1_ro04066 propionyl-CoA carboxylase.
     
 0.778
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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