Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Tpau_0183Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (558 aa)    
Predicted Functional Partners:
Tpau_0187
KEGG: mjl:Mjls_0069 phosphotransferase system, phosphocarrier protein HPr; TIGRFAM: phosphocarrier, HPr family; PFAM: phosphoryl transfer system HPr.
 
 0.999
Tpau_0186
KEGG: mkm:Mkms_0089 PTS system, fructose subfamily, IIC subunit; TIGRFAM: PTS system, fructose subfamily, IIC subunit; PTS system, fructose subfamily, IIA subunit; PTS system, fructose-specific, IIB subunnit; PFAM: phosphotransferase system PTS fructose- specific IIB subunit; phosphotransferase system EIIC; phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2.
 
  
 0.984
Tpau_0797
PFAM: sugar-specific permease EIIA 1 domain; KEGG: kse:Ksed_16940 PTS system N-acetylglucosamine- specific EIIA component.
 
 
 0.939
Tpau_0185
1-phosphofructokinase; KEGG: mkm:Mkms_0090 ribokinase-like domain- containing protein; TIGRFAM: 1-phosphofructokinase; PFAM: PfkB domain protein; Belongs to the carbohydrate kinase PfkB family.
 
  
 0.931
Tpau_0184
KEGG: mjl:Mjls_0072 DeoR family transcriptional regulator; PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; SMART: regulatory protein DeoR.
 
  
 0.833
Tpau_0795
KEGG: rha:RHA1_ro01550 protein-N(pi)- phosphohistidine--sugar phosphotransferase; PFAM: phosphotransferase system EIIC.
  
 0.727
Tpau_0796
PFAM: Phosphotransferase system EIIB/cysteine, phosphorylation site; KEGG: art:Arth_3515 phosphotransferase system PTS, EIIB protein.
 
  
 0.697
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
  
 0.582
Tpau_0182
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: mjl:Mjls_0601 glyoxalase/bleomycin resistance protein/dioxygenase.
       0.558
Tpau_3762
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
  
 0.556
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
Server load: medium (48%) [HD]