Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
Tpau_0187KEGG: mjl:Mjls_0069 phosphotransferase system, phosphocarrier protein HPr; TIGRFAM: phosphocarrier, HPr family; PFAM: phosphoryl transfer system HPr. (85 aa)    
Predicted Functional Partners:
Tpau_0183
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 0.999
Tpau_0186
KEGG: mkm:Mkms_0089 PTS system, fructose subfamily, IIC subunit; TIGRFAM: PTS system, fructose subfamily, IIC subunit; PTS system, fructose subfamily, IIA subunit; PTS system, fructose-specific, IIB subunnit; PFAM: phosphotransferase system PTS fructose- specific IIB subunit; phosphotransferase system EIIC; phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2.
 
 
 0.997
Tpau_0797
PFAM: sugar-specific permease EIIA 1 domain; KEGG: kse:Ksed_16940 PTS system N-acetylglucosamine- specific EIIA component.
 
 0.977
Tpau_0795
KEGG: rha:RHA1_ro01550 protein-N(pi)- phosphohistidine--sugar phosphotransferase; PFAM: phosphotransferase system EIIC.
  
 
 0.940
Tpau_0185
1-phosphofructokinase; KEGG: mkm:Mkms_0090 ribokinase-like domain- containing protein; TIGRFAM: 1-phosphofructokinase; PFAM: PfkB domain protein; Belongs to the carbohydrate kinase PfkB family.
 
  
 0.924
Tpau_3061
KEGG: sen:SACE_4439 LacI family transcription regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI.
   
 
 0.831
Tpau_3559
Transcriptional regulator, LacI family; KEGG: msm:MSMEG_6798 ribose operon repressor; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI.
   
 
 0.831
Tpau_0184
KEGG: mjl:Mjls_0072 DeoR family transcriptional regulator; PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; SMART: regulatory protein DeoR.
 
  
 0.826
rpsG
Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
  
    0.545
Tpau_0796
PFAM: Phosphotransferase system EIIB/cysteine, phosphorylation site; KEGG: art:Arth_3515 phosphotransferase system PTS, EIIB protein.
 
  
 0.493
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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