Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_0200KEGG: rer:RER_45540 MarR family transcriptional regulator; PFAM: regulatory protein MarR; SMART: regulatory protein MarR. (159 aa)    
Predicted Functional Partners:
Tpau_0199
KEGG: rha:RHA1_ro00326 hypothetical protein.
 
    0.818
Tpau_0198
PFAM: peptidase S58 DmpA; KEGG: fal:FRAAL5354 hypothetical protein.
       0.771
Tpau_0197
KEGG: mgi:Mflv_0488 hypothetical protein.
       0.652
Tpau_0201
KEGG: mav:MAV_1056 ATP-dependent DNA ligase; TIGRFAM: DNA polymerase LigD, polymerase domain protein; DNA ligase D, 3'-phosphoesterase domain protein; DNA polymerase LigD, ligase domain protein; PFAM: ATP dependent DNA ligase; DNA primase small subunit; ATP dependent DNA ligase domain protein; mRNA capping enzyme.
       0.628
ku
Ku protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
       0.418
Tpau_2752
Peroxiredoxin, Ohr subfamily; KEGG: mjl:Mjls_1204 OsmC family protein; TIGRFAM: peroxiredoxin, Ohr subfamily; PFAM: OsmC family protein.
  
 0.408
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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