Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_0215PFAM: protein of unknown function DUF1006; KEGG: kse:Ksed_08640 hypothetical protein. (385 aa)    
Predicted Functional Partners:
Tpau_0214
PFAM: NUDIX hydrolase; KEGG: art:Arth_0808 NUDIX hydrolase.
       0.778
Tpau_0213
TIGRFAM: L-serine dehydratase 1; KEGG: rha:RHA1_ro05336 L-serine ammonia-lyase; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family.
       0.648
Tpau_1099
Transcriptional regulator, MerR family; TIGRFAM: redox-sensitive transcriptional activator SoxR; PFAM: Transcription regulator MerR DNA binding; regulatory protein MerR; KEGG: rha:RHA1_ro05652 redox-sensitive transcriptional activator; SMART: regulatory protein MerR.
  
     0.486
Tpau_0212
PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: mab:MAB_4771 putative adenylate cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase.
       0.481
Tpau_1761
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
  
  
 0.426
Tpau_0765
KEGG: nfa:nfa34980 hypothetical protein.
 
     0.413
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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