Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_0246SMART: serine/threonine protein kinase; KEGG: sen:SACE_4230 serine/threonine protein kinase. (896 aa)    
Predicted Functional Partners:
Tpau_3480
Mycocerosate synthase., 6-deoxyerythronolide-B synthase; KEGG: sen:SACE_4141 type I modular polyketide synthase; PFAM: short-chain dehydrogenase/reductase SDR; Beta- ketoacyl synthase; KR domain protein; Acyl transferase; NAD-dependent epimerase/dehydratase; phosphopantetheine- binding.
 
  
 0.618
Tpau_3477
PFAM: Acyl transferase; KR domain protein; Beta- ketoacyl synthase; short-chain dehydrogenase/reductase SDR; NAD-dependent epimerase/dehydratase; phosphopantetheine-binding; KEGG: sgr:SGR_6073 putative type-I PKS.
 
  
 0.574
Tpau_1168
PFAM: Erythromycin esterase; KEGG: dra:DR_A0345 hypothetical protein.
  
    0.568
Tpau_0245
KEGG: fre:Franean1_0530 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase.
  
  
 0.535
Tpau_0039
KEGG: saq:Sare_3599 XRE family transcriptional regulator; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein.
  
 
 
 0.524
Tpau_0244
PFAM: protein of unknown function DUF214; KEGG: rop:ROP_61080 hypothetical membrane protein.
       0.489
Tpau_1167
KEGG: sgr:SGR_431 MerR family transcriptional regulator; PFAM: regulatory protein MerR; SMART: regulatory protein MerR.
  
   0.487
Tpau_3487
PFAM: protein of unknown function DUF1205; glycosyl transferase family 28; KEGG: sen:SACE_0726 glycosyl transferase, NDP-D- desosamine: 3-L-mycarosyl erythronolide B.
  
     0.481
Tpau_3481
PFAM: NDP-hexose 23-dehydratase; KEGG: svi:Svir_29870 NDP-hexose 2,3-dehydratase.
  
    0.472
Tpau_3476
KEGG: stp:Strop_2778 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase; Acyl transferase; KR domain protein; Thioesterase; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding.
 
  
 0.464
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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