Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_0356PFAM: fumarate lyase; Fumarase C-like; KEGG: aau:AAur_3794 aspartate ammonia-lyase. (481 aa)    
Predicted Functional Partners:
Tpau_2631
PFAM: Asparaginase/glutaminase; KEGG: rop:ROP_43680 putative L-asparaginase.
  
 
 0.960
Tpau_2011
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
    
 0.908
argH
KEGG: nfa:nfa19630 argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase.
     
0.907
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
     
 0.905
Tpau_1536
TIGRFAM: asparagine synthase (glutamine- hydrolyzing); KEGG: nfa:nfa17070 putative asparagine synthetase; PFAM: asparagine synthase; glutamine amidotransferase class-II.
     
 0.905
Tpau_3624
TIGRFAM: adenylosuccinate lyase; KEGG: rer:RER_10250 adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase-like; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
     
 0.905
pyrB
TIGRFAM: aspartate carbamoyltransferase; KEGG: mjl:Mjls_2404 aspartate carbamoyltransferase catalytic subunit; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
     
  0.900
Tpau_1211
2-oxoglutarate dehydrogenase, E1 subunit; KEGG: rha:RHA1_ro06012 alpha-ketoglutarate decarboxylase; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: Transketolase central region; dehydrogenase E1 component; catalytic domain of components of various dehydrogenase complexes.
    
 0.858
Tpau_1616
KEGG: rop:ROP_60750 glutamate decarboxylase; TIGRFAM: glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase; Belongs to the group II decarboxylase family.
     
 0.855
argG
TIGRFAM: argininosuccinate synthase; KEGG: lxx:Lxx21970 argininosuccinate synthase; PFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 2 subfamily.
     
 0.823
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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