Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Tpau_0466PFAM: protein of unknown function DUF218; KEGG: rer:RER_53690 hypothetical protein. (183 aa)    
Predicted Functional Partners:
Tpau_0467
Hypothetical protein.
       0.701
Tpau_0465
PFAM: protein of unknown function DUF224 cysteine- rich region domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: nfa:nfa54200 putative iron-sulphur-binding reductase.
       0.567
Tpau_0464
KEGG: mmi:MMAR_2661 hypothetical protein.
       0.442
Tpau_0468
Putative transcriptional regulator, TetR family; PFAM: regulatory protein TetR; Polyketide cyclase/dehydrase; KEGG: fal:FRAAL5132 TetR family transcriptional repressor.
       0.424
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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