| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Tpau_0558 | Tpau_0561 | Tpau_0558 | Tpau_0561 | KEGG: mva:Mvan_4969 hypothetical protein. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.521 |
| Tpau_0558 | Tpau_0562 | Tpau_0558 | Tpau_0562 | KEGG: mva:Mvan_4969 hypothetical protein. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.521 |
| Tpau_0558 | Tpau_0563 | Tpau_0558 | Tpau_0563 | KEGG: mva:Mvan_4969 hypothetical protein. | TIGRFAM:2-amino-4-hydroxy-6- hydroxymethyldihydropter idinepyrophosphokinase; KEGG: rop:ROP_43270 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin- pyrophosphokinase HPPK. | 0.521 |
| Tpau_0558 | Tpau_0564 | Tpau_0558 | Tpau_0564 | KEGG: mva:Mvan_4969 hypothetical protein. | KEGG: rop:ROP_43280 hypothetical membrane protein. | 0.421 |
| Tpau_0558 | folE | Tpau_0558 | Tpau_0560 | KEGG: mva:Mvan_4969 hypothetical protein. | TIGRFAM: GTP cyclohydrolase I; KEGG: mjl:Mjls_5155 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase. | 0.521 |
| Tpau_0558 | ftsH | Tpau_0558 | Tpau_0559 | KEGG: mva:Mvan_4969 hypothetical protein. | ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.521 |
| Tpau_0561 | Tpau_0558 | Tpau_0561 | Tpau_0558 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | KEGG: mva:Mvan_4969 hypothetical protein. | 0.521 |
| Tpau_0561 | Tpau_0562 | Tpau_0561 | Tpau_0562 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.999 |
| Tpau_0561 | Tpau_0563 | Tpau_0561 | Tpau_0563 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | TIGRFAM:2-amino-4-hydroxy-6- hydroxymethyldihydropter idinepyrophosphokinase; KEGG: rop:ROP_43270 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin- pyrophosphokinase HPPK. | 0.999 |
| Tpau_0561 | Tpau_0564 | Tpau_0561 | Tpau_0564 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | KEGG: rop:ROP_43280 hypothetical membrane protein. | 0.715 |
| Tpau_0561 | folE | Tpau_0561 | Tpau_0560 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | TIGRFAM: GTP cyclohydrolase I; KEGG: mjl:Mjls_5155 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase. | 0.995 |
| Tpau_0561 | ftsH | Tpau_0561 | Tpau_0559 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.886 |
| Tpau_0562 | Tpau_0558 | Tpau_0562 | Tpau_0558 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | KEGG: mva:Mvan_4969 hypothetical protein. | 0.521 |
| Tpau_0562 | Tpau_0561 | Tpau_0562 | Tpau_0561 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |
| Tpau_0562 | Tpau_0563 | Tpau_0562 | Tpau_0563 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | TIGRFAM:2-amino-4-hydroxy-6- hydroxymethyldihydropter idinepyrophosphokinase; KEGG: rop:ROP_43270 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin- pyrophosphokinase HPPK. | 0.999 |
| Tpau_0562 | Tpau_0564 | Tpau_0562 | Tpau_0564 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | KEGG: rop:ROP_43280 hypothetical membrane protein. | 0.715 |
| Tpau_0562 | folE | Tpau_0562 | Tpau_0560 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | TIGRFAM: GTP cyclohydrolase I; KEGG: mjl:Mjls_5155 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase. | 0.996 |
| Tpau_0562 | ftsH | Tpau_0562 | Tpau_0559 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.911 |
| Tpau_0563 | Tpau_0558 | Tpau_0563 | Tpau_0558 | TIGRFAM:2-amino-4-hydroxy-6- hydroxymethyldihydropter idinepyrophosphokinase; KEGG: rop:ROP_43270 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin- pyrophosphokinase HPPK. | KEGG: mva:Mvan_4969 hypothetical protein. | 0.521 |
| Tpau_0563 | Tpau_0561 | Tpau_0563 | Tpau_0561 | TIGRFAM:2-amino-4-hydroxy-6- hydroxymethyldihydropter idinepyrophosphokinase; KEGG: rop:ROP_43270 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin- pyrophosphokinase HPPK. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |